24 May 2018 Probing tissue multifractality for optical diagnosis of diabetic retinopathy
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Abstract
Diabetic Retinopathy (DR) is one of the most dominant diseases across the globe which causes blindness. In this manuscript, we have probed tissue multifractality in order to identify the submicron level changes in medium refractive indices due to progress of diabetic retinopathy from mild to severe stages. Hence the quantification of multifractal parameters like Hurst exponent (measurement of correlation) and width of singularity (measurement of heterogeneity) have been executed. As we proceed from healthy to different stages (mild, moderate and severe) of diabetic retinopathy, there are decrement of Hurst exponent value, whereas, width of singularity spectrum increases. In general, the use of multifractal analysis on in vivo diabetic retinopathy images lead to a diagnostic modality as a potential statistical biomarker.
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Sawon Pratiher, Sawon Pratiher, Sabyasachi Mukhopadhyay, Sabyasachi Mukhopadhyay, Sukanya Mukherjee, Sukanya Mukherjee, Ritwik Barman, Ritwik Barman, Gautham Pasupuleti, Gautham Pasupuleti, Jay Chhablani, Jay Chhablani, Prasanta K. Panigrahi, Prasanta K. Panigrahi, } "Probing tissue multifractality for optical diagnosis of diabetic retinopathy ", Proc. SPIE 10679, Optics, Photonics, and Digital Technologies for Imaging Applications V, 1067906 (24 May 2018); doi: 10.1117/12.2305454; https://doi.org/10.1117/12.2305454
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