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The paper discusses the fabrication and the test results of a blood urea nitrogen sensor (BUN) and a chloride sensor. The BUN sensor consists of a potentiometric ammonium ion sensor covered by a polymer membrane that contains the immobilized enzyme urease. The chloride sensor is a liquid membrane type electrode. Both electrodes are batch fabricated. The sensors are part of a multispecies sensor chip. The results of the sensor in aqueous solutions and blood will be given. Good uniformity and reproducibility is obtained. The BUN sensor has a linear range of 1 to 20 mM urea and a coefficient of variation of 3% in normal blood.
J. Van der Spiegel,I. R. Lauks,H. J. Wieck,N. Smit, andS. Cozzette
"Characteristics Of Microfabricated Ion Selective Electrodes", Proc. SPIE 1068, Catheter-Based Sensing and Imaging Technology, (8 August 1989); https://doi.org/10.1117/12.952155
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J. Van der Spiegel, I. R. Lauks, H. J. Wieck, N. Smit, S. Cozzette, "Characteristics Of Microfabricated Ion Selective Electrodes," Proc. SPIE 1068, Catheter-Based Sensing and Imaging Technology, (8 August 1989); https://doi.org/10.1117/12.952155