SNORW biosensor for measuring glucose level in blood samples

Vishnu Priye; Ritu Raj Singh; Soumya Kumari; Nishit Malviya

doi:10.1117/12.2306383

9 May 2018 SNORW biosensor for measuring glucose level in blood samples

Vishnu Priye, Ritu Raj Singh, Soumya Kumari, Nishit Malviya

Proceedings Volume 10680, Optical Sensing and Detection V; 1068015 (2018) https://doi.org/10.1117/12.2306383
Event: SPIE Photonics Europe, 2018, Strasbourg, France

Abstract

A silicon nanowire waveguide based glucose sensor has been proposed and analyzed. It uses minimal invasive approach to measure the glucose level in a very small blood sample, where, Ethylene-diamine-tetraacetic acid (EDTA) as an anticoagulant, sodium fluoride as preservative and blood sample measurand are added in the ratio of 8:1:1. As the glucose concentration in the blood sample varies, the refractive index (RI) of blood changes, accordingly the refractive index of the solution with 10% blood also gets altered, which in turn to deviated response of the biosensor. The prediction of glucose level is affirmed by taking this solution as a cladding measurand of waveguide. Silicon Nanowire Optical Rectangular Waveguide (SNORW) is proposed for the first time in bio-sensing application for the detection of blood glucose. It works on the principle of detecting changes in refractive index for various concentrations of glucose level ranging from 10 mg/dl to 200 mg/dl. Additionally, SNORW sensor characteristics are compared accordingly with the slot waveguide sensors.

Conference Presentation

Citation Download Citation

Vishnu Priye, Ritu Raj Singh, Soumya Kumari, and Nishit Malviya "SNORW biosensor for measuring glucose level in blood samples", Proc. SPIE 10680, Optical Sensing and Detection V, 1068015 (9 May 2018); https://doi.org/10.1117/12.2306383

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