9 May 2018 SNORW biosensor for measuring glucose level in blood samples
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Abstract
A silicon nanowire waveguide based glucose sensor has been proposed and analyzed. It uses minimal invasive approach to measure the glucose level in a very small blood sample, where, Ethylene-diamine-tetraacetic acid (EDTA) as an anticoagulant, sodium fluoride as preservative and blood sample measurand are added in the ratio of 8:1:1. As the glucose concentration in the blood sample varies, the refractive index (RI) of blood changes, accordingly the refractive index of the solution with 10% blood also gets altered, which in turn to deviated response of the biosensor. The prediction of glucose level is affirmed by taking this solution as a cladding measurand of waveguide. Silicon Nanowire Optical Rectangular Waveguide (SNORW) is proposed for the first time in bio-sensing application for the detection of blood glucose. It works on the principle of detecting changes in refractive index for various concentrations of glucose level ranging from 10 mg/dl to 200 mg/dl. Additionally, SNORW sensor characteristics are compared accordingly with the slot waveguide sensors.
Conference Presentation
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Vishnu Priye, Vishnu Priye, Ritu Raj Singh, Ritu Raj Singh, Soumya Kumari, Soumya Kumari, Nishit Malviya, Nishit Malviya, } "SNORW biosensor for measuring glucose level in blood samples", Proc. SPIE 10680, Optical Sensing and Detection V, 1068015 (9 May 2018); doi: 10.1117/12.2306383; https://doi.org/10.1117/12.2306383
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