28 May 2018 Numerical prediction and approximate inversion of optoacoustic signals in tissue phantoms
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Abstract
We illustrate a modular numerical approach that allows for the prediction of laser-generated optoacoustic signals in melanin doped PVA-H (polyvinyl alcohol hydrogel) tissue phantoms, geared towards experiments with dominantly absorbing, acoustically homogeneous media. We apply the numerical procedure to predict signals observed in the acoustic farfield and complement numerical simulations and laboratory measurements for an exemplary layered source volume configuration. Further, we address the inverse OA problem that facilitates the reconstruction of optical properties from measured OA signals for sufficiently facile problem setups.
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O. Melchert, O. Melchert, E. Blumenröther, E. Blumenröther, M. Wollweber, M. Wollweber, B. Roth, B. Roth, } "Numerical prediction and approximate inversion of optoacoustic signals in tissue phantoms", Proc. SPIE 10695, Optical Instrument Science, Technology, and Applications, 106950B (28 May 2018); doi: 10.1117/12.2314840; https://doi.org/10.1117/12.2314840
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