24 April 2018 Illuminating gene expression dynamics by optogenetics
Author Affiliations +
Proceedings Volume 10711, Biomedical Imaging and Sensing Conference; 107110K (2018) https://doi.org/10.1117/12.2311587
Event: SPIE Structured Light, 2018, Yokohama, Japan
Cells receive diverse signaling cues from their environment that trigger cascades of biochemical reactions in a dynamic manner. Live-cell imaging technologies have revealed dynamic patterns of gene activities; however it has been challenging to clarify how such dynamic information is delivered and decoded in complex networks of inter-cellular and inter-molecular interactions. The recent development of optogenetic technology with photo-sensitive proteins has changed this situation. In this talk, we introduce our recent efforts to visualize the flows of dynamic patterns in gene expression dynamics, which utilize methods combining single-cell imaging and optogenetics.
© (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Akihiro Isomura, Akihiro Isomura, } "Illuminating gene expression dynamics by optogenetics", Proc. SPIE 10711, Biomedical Imaging and Sensing Conference, 107110K (24 April 2018); doi: 10.1117/12.2311587; https://doi.org/10.1117/12.2311587

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