5 March 2018 Silicon photonic resonator for label-free bio-sensing application
Author Affiliations +
Proceedings Volume 10714, Third International Conference on Photonics Solutions (ICPS2017); 107140T (2018) https://doi.org/10.1117/12.2300961
Event: Third International Conference on Photonic Solutions, 2017, Pattaya, Thailand
In medical diagnostics there is an increasing demand for biosensors that can specifically detect biological analytes in a fluid. Especially label-free sensing, consistings of a transducer with biorecognition molecules immobilized on its surface without relying on fluorescent dye. In this paper we study the design and fabrication of a silicon nanowire photonic ring resonator and its feasibility as a biosensor. We have simulated and fabricated racetrack ring resonators which have a few tenths of micrometer gap, up to 0.5 μm between the input / output waveguides and the resonators. It is found that the devices can be designed with large Q factors. Sensitivity to biomaterial detection has been simulated for antibody (goat anti-mouse IgG) - antigen (mouse IgG) using 3-dimensional Finite Difference Time Domain technique. The simulated results show that the ring resonator has a response 15 nm resonance shift per refractive index unit. Antibody coating method is also discussed in this paper which can be applied to other antibody-antigen types.
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Suruk Udomsom, Suruk Udomsom, Ukrit Mankong, Ukrit Mankong, Nipon Theera-Umpon, Nipon Theera-Umpon, Nattapol Ittipratheep, Nattapol Ittipratheep, Toshimasa Umezawa, Toshimasa Umezawa, Atsushi Matsumoto, Atsushi Matsumoto, Naokatsu Yamamoto, Naokatsu Yamamoto, "Silicon photonic resonator for label-free bio-sensing application", Proc. SPIE 10714, Third International Conference on Photonics Solutions (ICPS2017), 107140T (5 March 2018); doi: 10.1117/12.2300961; https://doi.org/10.1117/12.2300961

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