26 April 2018 Application of virtual phase-shifting speckle-interferometry for detection of polymorphism in the Chlamydia trachomatis omp1 gene
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Abstract
Method of phase-shifting speckle-interferometry has been used as a new tool with high potency for modern bioinformatics. Virtual phase-shifting speckle-interferometry has been applied for detection of polymorphism in the of Chlamydia trachomatis omp1 gene. It has been shown, that suggested method is very sensitive to natural genetic mutations as single nucleotide polymorphism (SNP). Effectiveness of proposed method has been compared with effectiveness of the newest bioinformatic tools, based on nucleotide sequence alignment.
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Valentina A. Feodorova, Valentina A. Feodorova, Yury V. Saltykov , Yury V. Saltykov , Sergey S. Zaytsev, Sergey S. Zaytsev, Sergey S. Ulyanov, Sergey S. Ulyanov, Onega V. Ulianova, Onega V. Ulianova, } "Application of virtual phase-shifting speckle-interferometry for detection of polymorphism in the Chlamydia trachomatis omp1 gene", Proc. SPIE 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX, 107160M (26 April 2018); doi: 10.1117/12.2314700; https://doi.org/10.1117/12.2314700
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