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26 April 2018 Investigation of the surface morphology of biocompatible chitosan-based hydrogels and xerogels
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Abstract
Our biocompatible hydrogel systems obtained by the sol-gel technqiue and based on chitosan and silicon polyolates are promising for medical and biological applications. The surface microrelief of these sol-gel materials (hydrogels and xerogels) based on chitosan and silicon tetraglycerolate was explored by AFM and SEM. A significant influence of the component ratio in the mixed system on the morphology and surface profile of the hydrogels and xerogels prepared therefrom was established. An increased content of the structure-forming component (chitosan) in the system was shown to increase the roughness scale of the hydrogel surface and to promote the porosity of the xerogel structure.
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Yulia Yu. Zhuravleva, Olga N. Malinkina, and Anna B. Shipovskaya "Investigation of the surface morphology of biocompatible chitosan-based hydrogels and xerogels", Proc. SPIE 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX, 107161Y (26 April 2018); https://doi.org/10.1117/12.2315131
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