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26 April 2018 Highly localized laser-induced vascular responses
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Abstract
The assessment of functioning microcirculatory network implies usage of adequate tools for testing the network responses on local changes of vessels state. While there are well-developed and widely used methods, such as focal application of vasoactive substances, or electric stimulation, there is a need for a non-destructive (and ideally – non-contact) and local method of impact a single vessel in order to trigger the network responce.

In this paper, we investigate the possibility of applying the effect of a reversible change in the diameter of a blood vessel caused by laser radiation as a functional test of a microcirculatory system. For this purpose, we combine this effect with the method of micro-PIV (particle image velocimetry), which provides information on both the dynamics of blood flow in neighboring segments and the changes in their diameters.
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Elena S. Stiukhina, Maxim A. Kurochkin, Ivan V. Fedosov, and Dmitry E. Postnov "Highly localized laser-induced vascular responses", Proc. SPIE 10717, Saratov Fall Meeting 2017: Laser Physics and Photonics XVIII; and Computational Biophysics and Analysis of Biomedical Data IV, 107171Z (26 April 2018); https://doi.org/10.1117/12.2315072
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