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17 September 2018 System of biological crystals fibrillar networks polarization-correlation mapping
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Abstract
A new model of the correlation description of the optically anisotropic component of biological tissues is proposed. To characterize the transformation of the fibrillar network of laser radiation, a new parameter is used-the complex "twopoint" Stokes vector. The interconnections between the parameters of the "two-point" Stokes vector with the distributions of the optical axes and birefringence of the fibrillar network of biological tissue are found. A scheme of generalized Stokes polarimetry of microscopic images of histological sections of fibrillar biological tissues is developed. A technique for direct polarization measurement of the distributions of the real and imaginary parts of the "two-point" Stokes vector is proposed. Maps of phase distributions of the "two-point" Stokes vector of histological sections of the myocardium and endometrium. The sensitivity, specificity and balanced accuracy of the method of polarizationcorrelation mapping of fibrillar networks of biological crystals are determined. Within the framework of the statistical analysis of the phase maps of the "two-point" Stokes vector, histological sections of the myocardium and endometrium, objective criteria for diagnosing endometrial cancer have been found and an excellent balanced accuracy of the cause of death.
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M. Yu. Sakhnovskiy, A.-V. Syvokorovskaya, V. Martseniak, B. M. Bodnar, O. Tsyhykalo, A. V. Dubolazov, O. I. Olar, V. A. Ushenko, and P. M. Grygoryshyn "System of biological crystals fibrillar networks polarization-correlation mapping", Proc. SPIE 10752, Applications of Digital Image Processing XLI, 107522G (17 September 2018); https://doi.org/10.1117/12.2320511
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