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18 September 2018 Digital image capture for high-resolution medical x-ray diagnostics
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Abstract
We have demonstrated a high resolution (10 micron) X-ray scintillator plate as part of an indirect X-ray detection system. Scintillator plates are typically integrated with a 2-dimensional array of photodiodes based upon amorphous Si. This paper describes an alternative digital capture system that leverages low cost CCD/CMOS cameras. Our detector has a broad set of potential applications, however the initial target application is mammography. Full-field mammography mandates an imaging area of 180mm x 240mm or larger. Very large CCD/CMOS sensors have recently been developed for high resolution cameras, such as the 250-pixel Canon camera which has sensor dimensions of 202mm x 205mm, and could conceivably be matched to our high-resolution scintillator plate without any intervening optics for magnification. However, such large format CCD/CMOS sensors have limited availability because of low production yields and high cost considerations. On the other hand, small form (36mm x 24mm) and medium format (44mm x 33mm) CCD/CMOS-based photodiodes have become widely available at low cost due to their applications in the large markets of mobile devices and consumer cameras. We have therefore developed a simple optical scheme for utilizing four small or medium format CCD/CMOS cameras to capture a larger, high-resolution image. Current systems employed in screening mammography resolve tissue features of 75-100 microns. Suspicious features found during preliminary mammographic screenings are further investigated during diagnostic mammographic tests which use a high-resolution detector that is focused over the suspicious lesion. Typically, an area less than 100mm x 80mm, the current maximum size of our high-resolution scintillation plate, is interrogated. We show that diagnostic mammography, over an area of 100mm x 80mm, could be performed using our system with a feature resolution down to 7 microns.
Conference Presentation
© (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Theodore F. Morse, Nicholas Mostovych, Rajiv Gupta, Timothy Murphy, Peter Weber, Nerine Cherepy, Bernhard Adams, Thomas Bifano, Brian Stankus, Adil Akif, and Angus I. Kingon "Digital image capture for high-resolution medical x-ray diagnostics", Proc. SPIE 10763, Radiation Detectors in Medicine, Industry, and National Security XIX, 107630E (18 September 2018); https://doi.org/10.1117/12.2321166
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