Imaging through turbid media with wavefront modulated illumination full-field optical coherence microscopy

Michal Hamkalo; Dawid Borycki; Maciej Wojtkowski

doi:10.1117/12.2319616

7 September 2018 Imaging through turbid media with wavefront modulated illumination full-field optical coherence microscopy

Michal Hamkalo, Dawid Borycki, Maciej Wojtkowski

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Proceedings Volume 10834, Speckle 2018: VII International Conference on Speckle Metrology; 1083420 (2018) https://doi.org/10.1117/12.2319616
Event: SPECKLE 2018: VII International Conference on Speckle Metrology, 2018, Janów Podlaski, Poland

Abstract

Imaging deep inside the tissue still remains a challenge for all microscopic techniques. Imaging using coherent illumination is even more challenging due to unwanted effects like speckle formation causing significant loss of imaging contrast. In our work we propose a solution to this problem by controlling the spatial distribution of phase of light illuminating the sample. In newly developed optical set-up the beam illuminating the sample first is passing through SLM that enables to fully control projected light patterns. The interferometric setup enables to perform 3D full field OCM imaging. We present the results from controlled wavefront illumination and its ability to image through scattering layers. The ultimate goal of our techniques is to create new imaging method applicable for biological 3D imaging in turbid medium.

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Michal Hamkalo, Dawid Borycki, and Maciej Wojtkowski "Imaging through turbid media with wavefront modulated illumination full-field optical coherence microscopy", Proc. SPIE 10834, Speckle 2018: VII International Conference on Speckle Metrology, 1083420 (7 September 2018); https://doi.org/10.1117/12.2319616

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KEYWORDS

Scattering

Wavefronts

Diffusers

Spatial light modulators

Image quality

Speckle

Light scattering

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