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26 February 2019 Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging
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Abstract
We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.
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Tianshi Wang, Tom Pfeiffer, Joost Daemen, Frits Mastik, Wolfgang Wieser, A. F. W. van der Steen, Robert Huber, and Gijs van Soest "Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging ", Proc. SPIE 10855, Diagnostic and Therapeutic Applications of Light in Cardiology 2019, 1085503 (26 February 2019); https://doi.org/10.1117/12.2506151
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