Lacrimal canaliculus imaging by dynamic OCT using extrinsic contrast agent

Reiko Yoshimura; Dong-hak Choi; Masahiro Fujimoto; Akihito Uji; Fumiko Hiwatashi; Kohji Ohbayashi

doi:10.1117/12.2508137

28 February 2019 Lacrimal canaliculus imaging by dynamic OCT using extrinsic contrast agent

Reiko Yoshimura, Dong-hak Choi, Masahiro Fujimoto, Akihito Uji, Fumiko Hiwatashi, Kohji Ohbayashi

Proceedings Volume 10858, Ophthalmic Technologies XXIX; 108581H (2019) https://doi.org/10.1117/12.2508137
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

In this study, the human lacrimal canaliculus (LC), an important segment of the lacrimal drainage system, was imaged using dynamic optical coherence tomography (D-OCT) and the 3D structure of the LC was rendered. In D-OCT system, a turbid commercial ophthalmic solution was used as an extrinsic contrast agent. The lumen boundary of the LC appeared clearer in D-OCT images compared with simple static OCT images, making segmentation easier. D-OCT was performed by calculating the sum of the squared differences of intensities with two different normalization parameters. By color-combining these two D-OCT images and static OCT image, using image calculation software, the contrast agent and the lumen boundary can be clearly separated. 3D volumetric images of the LCs are demonstrated.

Citation Download Citation

Reiko Yoshimura, Dong-hak Choi, Masahiro Fujimoto, Akihito Uji, Fumiko Hiwatashi, and Kohji Ohbayashi "Lacrimal canaliculus imaging by dynamic OCT using extrinsic contrast agent", Proc. SPIE 10858, Ophthalmic Technologies XXIX, 108581H (28 February 2019); https://doi.org/10.1117/12.2508137

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