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22 February 2019 Line-field confocal optical coherence tomography
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Abstract
We present an improved time-domain optical coherence tomography technique designed for ultrahigh-resolution B-scan imaging in real-time. The technique, called line-field confocal optical coherence tomography, is based on a Linnik-type interference microscope with line illumination using a supercontinuum laser and line detection using a line-scan camera. Bscan imaging with dynamic focusing is achieved by acquiring multiple A-scans in parallel. In vivo cellular level resolution imaging of skin is demonstrated at 10 frame/s with a penetration depth of ∼ 500 μm, with a spatial resolution of 1.3 μm × 1.1 μm (transverse × axial).
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Jonas Ogien, Olivier Levecq, Hicham Azimani, Arthur David, Weikai Xue, David Siret, Jean-Luc Perrot, and Arnaud Dubois "Line-field confocal optical coherence tomography", Proc. SPIE 10867, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII, 108670U (22 February 2019); doi: 10.1117/12.2507244; https://doi.org/10.1117/12.2507244
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