Simultaneous bright and dark field OCT with a polarization sensitive detection (Conference Presentation)

Pablo Eugui; Conrad Merkle; Danielle J. Harper; Antonia Lichtenegger; Marco Augustin; Martina Muck; Adelheid Wöhrer; Christoph K. Hitzenberger; Bernhard Baumann

doi:10.1117/12.2511454

4 March 2019 Simultaneous bright and dark field OCT with a polarization sensitive detection (Conference Presentation)

Pablo Eugui , Conrad Merkle, Danielle J. Harper, Antonia Lichtenegger, Marco Augustin, Martina Muck, Adelheid Wöhrer, Christoph K. Hitzenberger, Bernhard Baumann

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Proceedings Volume 10867, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII; 108671T (2019) https://doi.org/10.1117/12.2511454
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

A polarization sensitive extension was implemented into our bright and dark field optical coherence tomography (BRAD-OCT) system. The few-mode fiber detection enables the analysis of the scattering profiles of biological tissues by sensing the sample backscattering information at larger angles through the different fiber modes, enabling simultaneous detection of the bright and dark field. Since the polarization state of light scattered at different angles strongly depends on the tissue microstructure, the polarization sensitive detection improves the imaging capabilities of BRAD-OCT. The system performance was evaluated in phantoms of differently sized microparticles, showing different polarization characteristics for the different fiber modes. Preliminary analysis has been performed in ex vivo brain tissue, where stokes vectors analysis of the different modal images reconstructed by our BRAD-OCT setup indicates that polarization sensitive in combination with BRAD detection is a promising tool for investigating the scattering properties of biological tissues.

Conference Presentation

Citation Download Citation

Pablo Eugui , Conrad Merkle, Danielle J. Harper, Antonia Lichtenegger, Marco Augustin, Martina Muck, Adelheid Wöhrer, Christoph K. Hitzenberger, and Bernhard Baumann "Simultaneous bright and dark field OCT with a polarization sensitive detection (Conference Presentation)", Proc. SPIE 10867, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII, 108671T (4 March 2019); https://doi.org/10.1117/12.2511454

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KEYWORDS

Polarization

Optical coherence tomography

Tissues

Biological research

Light scattering

Scattering

Backscatter

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