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22 February 2019 Thermo-elastic optical coherence tomography
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Abstract
The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. We investigate the thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. An analysis of the results shows that the displacement is dominated by the optical absorption. By tuning the excitation wavelength, thermo-elastic displacement spectrum can be extracted, showing the similar features as optical absorption spectrum. By choosing proper excitation wavelength, targeted tissue type can be highlighted, which further enables a new imaging modality, so called thermo-elastic OCT.
Conference Presentation
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Tianshi Wang, Tom Pfeiffer, Wolfgang Wieser, Heleen van Beusekom, Wolfgang Draxinger, Antonius F. W. van der Steen, Robert Huber, and Gijs van Soest "Thermo-elastic optical coherence tomography", Proc. SPIE 10867, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII, 108672C (22 February 2019); doi: 10.1117/12.2508852; https://doi.org/10.1117/12.2508852
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