Multi-wavelength dual-detection channel system for time-resolved near-infrared spectroscopy

Marco Renna; Mauro Buttafava; Anurag Behera; Marta Zanoletti; Laura Di Sieno; Alberto Dalla Mora; Davide Contini; Alberto Tosi

doi:10.1117/12.2509706

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1 March 2019 Multi-wavelength dual-detection channel system for time-resolved near-infrared spectroscopy

Marco Renna, Mauro Buttafava, Anurag Behera, Marta Zanoletti, Laura Di Sieno, Alberto Dalla Mora, Davide Contini, Alberto Tosi

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Proceedings Volume 10874, Optical Tomography and Spectroscopy of Tissue XIII; 1087408 (2019) https://doi.org/10.1117/12.2509706
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

We present a new full-custom instrument for time-domain diffuse optical spectroscopy developed within Horizon 2020 LUCA (Laser and Ultrasound Co-Analyzer for thyroid nodules) project. It features eight different picosecond diode lasers (in the 635 - 1050 nm range), two 1.3 × 1.3 mm² active-area SiPMs (Silicon PhotoMultipliers) working in single-photon mode and two 10 ps resolution time-to-digital converters. A custom FPGA-based control board manages the instrument and communicates with an external computer via USB connection. The instrument proved state-of-the-art performance: an instrument response function narrower than 160 ps (fullwidth at half-maximum), a long-term measurement stability better than 1%, and an output average optical power higher than 1 mW at 40 MHz. The instrument has been validated with phantom measurements.

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Marco Renna, Mauro Buttafava, Anurag Behera, Marta Zanoletti, Laura Di Sieno, Alberto Dalla Mora, Davide Contini, and Alberto Tosi "Multi-wavelength dual-detection channel system for time-resolved near-infrared spectroscopy", Proc. SPIE 10874, Optical Tomography and Spectroscopy of Tissue XIII, 1087408 (1 March 2019); https://doi.org/10.1117/12.2509706

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