Extraction of tissue optical parameters from diffuse reflectance measurements with a new able to count derivatives inverse Monte Carlo method

Alexander V. Lappa; Anastasiya E. Anchugova; Darina Yu Shakaeva

doi:10.1117/12.2507879

1 March 2019 Extraction of tissue optical parameters from diffuse reflectance measurements with a new able to count derivatives inverse Monte Carlo method

Alexander V. Lappa, Anastasiya E. Anchugova, Darina Yu Shakaeva

Author Affiliations +

Proceedings Volume 10876, Optical Interactions with Tissue and Cells XXX; 1087609 (2019) https://doi.org/10.1117/12.2507879
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

A new method for non-invasive determination of optical parameters (absorption and reduced scattering coefficients) of biological tissues from diffuse reflectance measurements with a multifiber probe is presented. For extraction of the parameters, we use a priori estimations not only of signals of detectors, but also their parameter derivatives that increases accuracy of the extraction. This estimation is performed using a new non-analog Monte Carlo algorithm which allows us to calculate the signals and derivatives simultaneously for a given large set of optical parameters. Experimental testing has shown the measured coefficients provide a good prediction of both light reflection and penetration. Application of the method to some biological tissues are presented.

Conference Presentation

Citation Download Citation

Alexander V. Lappa, Anastasiya E. Anchugova, and Darina Yu Shakaeva "Extraction of tissue optical parameters from diffuse reflectance measurements with a new able to count derivatives inverse Monte Carlo method", Proc. SPIE 10876, Optical Interactions with Tissue and Cells XXX, 1087609 (1 March 2019); https://doi.org/10.1117/12.2507879

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