Exogenous agent diffusivity in tissues as a biomarker of diabetes mellitus pathology

Daria K. Tuchina; Alexey N. Bashkatov; Alla B. Bucharskaya; Valery V. Tuchin

doi:10.1117/12.2506644

1 March 2019 Exogenous agent diffusivity in tissues as a biomarker of diabetes mellitus pathology

Daria K. Tuchina, Alexey N. Bashkatov, Alla B. Bucharskaya, Valery V. Tuchin

Proceedings Volume 10877, Dynamics and Fluctuations in Biomedical Photonics XVI; 108770X (2019) https://doi.org/10.1117/12.2506644
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

The study offers a possibility to use such biocompatible chemical as glycerol as a biomarker for early diagnostics of diabetes mellitus complications, in particular, for assessing the degree of myocardial lesion evidence by the stage of skin glycation during diabetes development and treatment. The study was aimed to find the difference in glycerol permeability through rat soft tissues of control and diabetic groups in order to show the possibility of glycerol usage as a biomarker of diabetes impact on different organs. The investigation presents transition the experimental studies from ex vivo to in vivo conditions.

Citation Download Citation

Daria K. Tuchina, Alexey N. Bashkatov, Alla B. Bucharskaya, and Valery V. Tuchin "Exogenous agent diffusivity in tissues as a biomarker of diabetes mellitus pathology", Proc. SPIE 10877, Dynamics and Fluctuations in Biomedical Photonics XVI, 108770X (1 March 2019); https://doi.org/10.1117/12.2506644

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