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22 February 2019 Differentiation of collagens I, II, and III by second order susceptibility imaging
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Abstract
Second order susceptibility (SOS) microscopy is used as a contrast mechanism for distinguishing types I and III collagen in tissues. In addition, relative proportion of collagen type was determined by analyzing the histograms of SOS ratios. Our results show that second order susceptibility is an effective metric for differentiating types I and III collagen without extrinsic labeling.
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Sheng-Lin Lee, Chiu-Mei Hsueh, Ya-Der Huang, Hsuan-Shu Lee, and Chen-Yuan Dong "Differentiation of collagens I, II, and III by second order susceptibility imaging", Proc. SPIE 10882, Multiphoton Microscopy in the Biomedical Sciences XIX, 1088235 (22 February 2019); https://doi.org/10.1117/12.2507168
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