Non-destructive real-time monitoring of brain tumor exception by combining high-frequency ultrasounds with infrared spectroscopy

Georgios Th. Karagiannis; Stamatios A. Amanatiadis; Georgios K. Apostolidis

doi:10.1117/12.2510451

21 February 2019 Non-destructive real-time monitoring of brain tumor exception by combining high-frequency ultrasounds with infrared spectroscopy

Georgios Th. Karagiannis, Stamatios A. Amanatiadis, Georgios K. Apostolidis

Author Affiliations +

Proceedings Volume 10883, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXVI; 108830Z (2019) https://doi.org/10.1117/12.2510451
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

The purpose of the current paper is the development of a non-destructive imaging system for diagnostic purposes, consisting of ultrasonic transducers of high frequency and an infrared spectrometer, enabling the monitoring of the brain spatial variation and the detection of cancerous cells spreading to healthy tissues during the neurosur- gical tumor exception. Ultrasound utilization during the neurosurgery, where a part of the skull is temporarily removed, is able to provide a new perspective on the imaging techniques. The proposed device combines trans- ducers of different center frequencies in order to achieve sufficient penetration depth inside the brain and fine spatial resolution. Moreover, the infrared spectroscopy technique is utilized and combined with the ultrasound to achieve the recognition of the cancerous cells from their infrared fingerprint. The drawback of the poor penetration depth of the infrared electromagnetic waves is overcome by inserting a small diameter probe near the location of the main tumor. The probe is integrated into the same structure as the ultrasound device to receive both signals from the identical spot. Finally, advanced signal processing techniques are used to maximize separately the information of the independent systems, while the data fusion will be attempted.

Conference Presentation

Citation Download Citation

Georgios Th. Karagiannis, Stamatios A. Amanatiadis, and Georgios K. Apostolidis "Non-destructive real-time monitoring of brain tumor exception by combining high-frequency ultrasounds with infrared spectroscopy", Proc. SPIE 10883, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXVI, 108830Z (21 February 2019); https://doi.org/10.1117/12.2510451

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