25 May 1989 True Color Image Analysis For Determination Of Bone Growth In Fluorochromic Biopsies
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Abstract
A true color imaging technique has been developed for analysis of microscopic fluorochromic bone biopsy images to quantify new bone growth. The technique searches for specified colors in a medical image for quantification of areas of interest. Based on a user supplied training set, a multispectral classification of pixel values is performed and used for segmenting the image. Good results were obtained when compared to manual tracings of new bone growth performed by an orthopedic surgeon. At a 95% confidence level, the hypothesis that there is no difference between the two methods can be accepted. Work is in progress to test bone biopsies with different colored stains and further optimize the analysis process using three-dimensional spectral ordering techniques.
© (1989) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
R. J. Madachy, R. J. Madachy, L. Chotivichit, L. Chotivichit, H. K. Huang, H. K. Huang, E. E. Johnson, E. E. Johnson, } "True Color Image Analysis For Determination Of Bone Growth In Fluorochromic Biopsies", Proc. SPIE 1092, Medical Imaging III: Image Processing, (25 May 1989); doi: 10.1117/12.953254; https://doi.org/10.1117/12.953254
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