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22 March 2019 Digital optical microscope (housing inside biosafety cabinet): a promising imaging technology for micro- and cell-biology, and histopathology
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Abstract
Conventional laboratory activities for research studies, more specifically in Biology and histopathology, involves back and forth movement of biological or tissue specimen all around the laboratory workspace - from Biosafety Cabinet (BSC) to workbench of microscopy imaging unit. This mobility imposes a serious concern of contamination of the biological specimen. We study design and develop of an optical microscopic imaging system - that can be adapted inside BSC - which remains as a challenge from technological aspects. This (automated) system with motion control in all 3-directions facilitates recording as well as observation of the biological procedure (in real time) being performed inside BSC. Experimental validation studies were carried out in a diverse biological specimen and demonstrate that this imaging technology facilitates study of miniscule biological specimen (cells and bacteria) not only easy but also enable to undertake sophisticated biological/clinical procedures.
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Anamika Elizabeth Kujur, Rinsa S. R., and Mayanglambam Suheshkumar Singh "Digital optical microscope (housing inside biosafety cabinet): a promising imaging technology for micro- and cell-biology, and histopathology", Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 109483T (22 March 2019); https://doi.org/10.1117/12.2502117
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