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1 March 2019 Deep learning based guidewire segmentation in x-ray images
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X-ray fluoroscopy is commonly used during liver embolization procedures to guide intravascular devices (e.g. guidewire and catheter) to the branches of the hepatic arteries feeding tumors. A vascular roadmap can be created to provide a reference for the device position. Recently, techniques have been developed to create dynamic vessel masks to compensate for respiratory motion. In order to superimpose the intravascular guidewire onto the vessel mask, robust segmentation is required. Commonly used techniques often use mask subtraction to isolate the device in x-ray images. However, this is not suitable due to the motion in liver applications. The proposed method uses a deep convolutional neural network to segment the guidewire in native (unsubtracted) x-ray images. The neural network uses an encoder / decoder structure, which is based on the VGG-16 network. To create a large dataset of annotated images, simulated images were created based on 3D digital subtraction angiography acquisitions of hepatic arteries in porcine studies. Random guidewire shapes were generated within the vascular volume and superimposed on the original non-contrast projection images. The network was trained using a set of 56,768 images created from 10 acquisitions. The segmentation results of the trained network were compared to a mask-subtraction-based algorithm for an independent validation data set. The deep learning algorithm (Dice = 58.1%, false negative rate (FNR) = 9.6%) outperformed the subtraction technique (Dice = 23.7%, FNR = 40.8%). This study shows that the deep learning approach is suitable for robust segmentation of curvilinear structures such as guidewires and could be used to superimpose the segmented device on dynamic roadmaps.
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Martin G. Wagner, Paul Laeseke, and Michael A. Speidel "Deep learning based guidewire segmentation in x-ray images ", Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 1094844 (1 March 2019);

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