Paper
1 March 2019 Visibility guided phase contrast denoising
Brandon Nelson, Thomas Koenig, Elisabeth Shanblatt, Shuai Leng, Cynthia McCollough
Author Affiliations +
Abstract
Talbot-Lau grating interferometry enables the use of clinical x-ray tubes for phase contrast imaging, greatly broadening its utility for both laboratory and preclinical applications. However, phase contrast measurements made in porous or highly heterogeneous media are negatively impacted by low visibility, the interferometer signal amplitude used to calculate relative phase shifts. While this loss in visibility is the source of dark field contrast it presents an additional source of noise in phase images. In this work, we develop a method to use normalized visibility images as the weighting matrix for denoising the corresponding phase contrast images. By using the visibility to guide filtering, the resulting denoised images are locally smoothed in regions of low visibility while maintaining spatial detail in regions of high visibility. This work demonstrates how the complementary properties of the dark field signal in grating interferometry can be leveraged to improve image quality in phase contrast images and presents an application in preclinical lung micro-CT.
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Brandon Nelson, Thomas Koenig, Elisabeth Shanblatt, Shuai Leng, and Cynthia McCollough "Visibility guided phase contrast denoising", Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 109484V (1 March 2019); https://doi.org/10.1117/12.2511212
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KEYWORDS
Visibility

Denoising

Phase contrast

Lung

Absorption

Image filtering

Tissues

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