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12 March 2019 Usefulness of the in vivo large field of view confocal line scanning ophthalmoscope in murine
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Abstract
Mouse is one of the most common animal models used in retinal researching, and obtaining its fundus images in vivo have significant significance for finding out formation and development mechanism of retinopathy, resolution and field-of-view are the key in fundus imaging. In this paper, we present an ophthalmoscope based on line scanning confocal technology, which utilizes one-dimension scanning line beam to increase image resolution and frame rate, it could capture mouse fundus at 1730*1730 μm field of view and 24 fps frame rate, retinal capillaries and vessels could be distinguished through reflectance and fluorescent images.
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Wen Kong, Wanyue Li, Feng Gao, Xingjie Jin, Jinyu Fan, and Guohua Shi "Usefulness of the in vivo large field of view confocal line scanning ophthalmoscope in murine", Proc. SPIE 11023, Fifth Symposium on Novel Optoelectronic Detection Technology and Application, 1102349 (12 March 2019); https://doi.org/10.1117/12.2521107
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