Real-time detection of BSA concentration based on a Mach-Zehnder interferometric biosensor

Zhitian Han; Wanjun Zheng; Bing Sun

doi:10.1117/12.2522635

Translator Disclaimer

14 February 2019 Real-time detection of BSA concentration based on a Mach-Zehnder interferometric biosensor

Zhitian Han, Wanjun Zheng, Bing Sun

Author Affiliations +

Proceedings Volume 11048, 17th International Conference on Optical Communications and Networks (ICOCN2018); 110484G (2019) https://doi.org/10.1117/12.2522635
Event: 17th International Conference on Optical Communications and Networks (ICOCN2018), 2018, Zhuhai, China

Abstract

A label-free optical fiber biosensor based on a Mach-Zehnder interferometer for real-time bovine serum albumin (BSA) concentration detection has been proposed and experimentally demonstrated. An air microcavity has been fabricated by means of splicing a segment of microfiber between two single mode fibers (SMFs) with appropriate offset such that it acts as a microfluidic channel, where external media can directly interact with the guided light. Experimental results show a high sensitivity of -15.56 nm/(mg/mL).

Citation Download Citation

Zhitian Han, Wanjun Zheng, and Bing Sun "Real-time detection of BSA concentration based on a Mach-Zehnder interferometric biosensor", Proc. SPIE 11048, 17th International Conference on Optical Communications and Networks (ICOCN2018), 110484G (14 February 2019); https://doi.org/10.1117/12.2522635

ACCESS THE FULL ARTICLE