The interaction of the europium complex with human serum albumin

Anastasiia V. Kharcheva; Mariya A. Kapitonova; Oleg K. Farat; Nataliya E. Borisova; Svetlana V. Patsaeva

doi:10.1117/12.2523257

3 June 2019 The interaction of the europium complex with human serum albumin

Anastasiia V. Kharcheva, Mariya A. Kapitonova, Oleg K. Farat, Nataliya E. Borisova, Svetlana V. Patsaeva

Proceedings Volume 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine; 110651P (2019) https://doi.org/10.1117/12.2523257
Event: International Symposium on Optics and Biophotonics VI: Saratov Fall Meeting 2018, 2018, Saratov, Russian Federation

Abstract

Investigation of proteins interactions with luminescent europium complex is interesting for the practical task of sensitive protein detection, as well as to study fundamental problems of peptide-lanthanide interplay. Presented work is devoted to examine the spectroscopic properties of europium complex (europium trinitrate (2,2'-bipyridyl-6,6'- dikarbonilazandiil)tetrakis (methylene) phosphonate) and to study its interaction with human serum albumin using various spectroscopic techniques. This complex has unique optical ability such as high values of the phosphorescence intensity in aqueous solutions, which exceeds the intensity of many other known coordination complexes of rare earth elements.

Citation Download Citation

Anastasiia V. Kharcheva, Mariya A. Kapitonova, Oleg K. Farat, Nataliya E. Borisova, and Svetlana V. Patsaeva "The interaction of the europium complex with human serum albumin", Proc. SPIE 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, 110651P (3 June 2019); https://doi.org/10.1117/12.2523257

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