Preliminary investigation of optimization-based image reconstruction for TOF PET with sparse configurations

Zheng Zhang; Buxin Chen; Amy E. Perkins; Chien-Min Kao; Emil Y. Sidky; Ravindra M. Manjeshwar; Xiaochuan Pan

doi:10.1117/12.2534846

28 May 2019 Preliminary investigation of optimization-based image reconstruction for TOF PET with sparse configurations

Zheng Zhang, Buxin Chen, Amy E. Perkins, Chien-Min Kao, Emil Y. Sidky, Ravindra M. Manjeshwar, Xiaochuan Pan

Proceedings Volume 11072, 15th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine; 110720L (2019) https://doi.org/10.1117/12.2534846
Event: Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine, 2019, Philadelphia, United States

Abstract

In this work, we investigate and characterize optimization-based image reconstruction from list-mode TOFPET data collected by using a digital TOF-PET scanner with reduced detectors, while seeking possibly to maintain the image quality and volume coverage. In particular, we focused on two patterns of sparse configurations, in both of which the total number of crystals is reduced to 50% of the corresponding clinical TOF-PET scanner. The reconstruction problem from data of the two sparse configurations is formulated as the solution to an image-TV-constrained, data-KLminimization optimization problem, and the image is reconstructed by use of an algorithm tailored from a Chambolle and Pock (CP) algorithm through solving the optimization problem. The characteristics of each sparse configuration was investigated by assessing the corresponding reconstructions visually and quantitatively. Results of the study suggest that certain sparse TOF-PET configurations may yield images with quality and volume coverage comparable to that obtained with current clinical TOF-PET scanner that has densely populated detectors.

Citation Download Citation

Zheng Zhang, Buxin Chen, Amy E. Perkins, Chien-Min Kao, Emil Y. Sidky, Ravindra M. Manjeshwar, and Xiaochuan Pan "Preliminary investigation of optimization-based image reconstruction for TOF PET with sparse configurations", Proc. SPIE 11072, 15th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine, 110720L (28 May 2019); https://doi.org/10.1117/12.2534846

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