Blood oxygenation in buried flaps: a bi-layer reconstruction

Audrey Dot; Anne Planat-Chrétien; Mathieu Perriollat; Michel Berger; Rodolphe Lartizien; Maxime Henry; Georges Bettega; Jean-Luc Coll

doi:10.1117/12.2527176

11 July 2019 Blood oxygenation in buried flaps: a bi-layer reconstruction

Audrey Dot, Anne Planat-Chrétien, Mathieu Perriollat, Michel Berger, Rodolphe Lartizien, Maxime Henry, Georges Bettega, Jean-Luc Coll

Author Affiliations +

Proceedings Volume 11074, Diffuse Optical Spectroscopy and Imaging VII; 1107427 (2019) https://doi.org/10.1117/12.2527176
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

Blood oxygenation in depth is a critical parameter to be monitored in many clinical applications. We are developing a pre-clinical instrument to monitor oxygenation up to 1.5 cm deep in biological tissues. The measures, based on time of ight, are in vivo, non invasive and without injection of any contrast agent. Developments have been implemented in a tomographic reconstruction algorithm to make it reconstruct chromophores by layers. These developments are presented here along with simulations we used to set up the algorithm. Buried aps on 20 pigs were undergone for pre-clinical tests of our reconstruction algorithm and instrument.

Citation Download Citation

Audrey Dot, Anne Planat-Chrétien, Mathieu Perriollat, Michel Berger, Rodolphe Lartizien, Maxime Henry, Georges Bettega, and Jean-Luc Coll "Blood oxygenation in buried flaps: a bi-layer reconstruction", Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 1107427 (11 July 2019); https://doi.org/10.1117/12.2527176

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