Hyperspectral optical coherence tomography: a tool for in vivo visualization of melanin in the retinal pigment epithelium

Danielle J. Harper; Thomas Konegger; Kornelia Schützenberger; Marco Augustin; Martin Glösmann; Antonia Lichtenegger; Pablo Eugui; Christoph K. Hitzenberger; Bernhard Baumann

doi:10.1117/12.2526059

19 July 2019 Hyperspectral optical coherence tomography: a tool for in vivo visualization of melanin in the retinal pigment epithelium

Danielle J. Harper, Thomas Konegger, Kornelia Schützenberger, Marco Augustin, Martin Glösmann, Antonia Lichtenegger, Pablo Eugui, Christoph K. Hitzenberger, Bernhard Baumann

Author Affiliations +

Proceedings Volume 11078, Optical Coherence Imaging Techniques and Imaging in Scattering Media III; 110780K (2019) https://doi.org/10.1117/12.2526059
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

A post-processing pipeline was created for white light optical coherence tomography, resulting in depth-resolved hyperspectral imaging. This method was tested on both melanin phantoms and in the RPE of rodent eyes, showing that due to its granular nature, melanin can be detected in this manner.

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Danielle J. Harper, Thomas Konegger, Kornelia Schützenberger, Marco Augustin, Martin Glösmann, Antonia Lichtenegger, Pablo Eugui, Christoph K. Hitzenberger, and Bernhard Baumann "Hyperspectral optical coherence tomography: a tool for in vivo visualization of melanin in the retinal pigment epithelium ", Proc. SPIE 11078, Optical Coherence Imaging Techniques and Imaging in Scattering Media III, 110780K (19 July 2019); https://doi.org/10.1117/12.2526059

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