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19 July 2019 MHz OCT angiography for 60 degree retinal imaging and microscopic choriocapillaris imaging
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Abstract
The choriocappilaris layer is considered to be one of the first retinal layers affected in age related macular degeneration and other retinal diseases [1]. Imaging this fine vascular layer below the retinal pigment epithelium (RPE) with optical coherence tomography angiography (OCTA) has been very challenging due to the high scattering and absorption of the RPE. In OCTA higher inter B-scan times increase the sensitivity for slow motion and hence improve the contrast of fine vessels. However, it was demonstrated that for the choriocappilaris the opposite is the case [2]. Novel swept source laser technology enables acquiring images at A-scan-rates of 1.7 million A-scans per second, which is approx. 17 times faster than the fastest commercially available OCT devices [3, 4]. OCTA images of the human macula with different inter B-scan times were acquired and compared. The same prototype system was also used to acquire single shot wide-field OCTA images with up to 60 degree field of view.
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
M. Niederleithner, L. Ginner, M. Salas, H. Ren, M. A. Arain, R. Williams, W. Drexler, R. A. Leitgeb, and T. Schmoll "MHz OCT angiography for 60 degree retinal imaging and microscopic choriocapillaris imaging", Proc. SPIE 11078, Optical Coherence Imaging Techniques and Imaging in Scattering Media III, 110781D (19 July 2019); https://doi.org/10.1117/12.2527079
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