Analysis of changes in blood flow oscillations under different probe pressure using laser Doppler spectrum decomposition

Igor O. Kozlov; Evgeny A. Zherebtsov; Mikhail A. Mezentsev; Valery V. Shupletsov; Elena V. Potapova; Angelina I. Zherebtsova; Viktor V. Dremin; Andrey V. Dunaev; Igor V. Meglinski

doi:10.1117/12.2527040

22 July 2019 Analysis of changes in blood flow oscillations under different probe pressure using laser Doppler spectrum decomposition

Igor O. Kozlov, Evgeny A. Zherebtsov, Mikhail A. Mezentsev, Valery V. Shupletsov, Elena V. Potapova, Angelina I. Zherebtsova, Viktor V. Dremin, Andrey V. Dunaev, Igor V. Meglinski

Author Affiliations +

Proceedings Volume 11079, Medical Laser Applications and Laser-Tissue Interactions IX; 110791Q (2019) https://doi.org/10.1117/12.2527040
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

Presently, in the modern laser Doppler flowmetry (LDF) the distribution of blood perfusion and its changes along the Doppler shift frequencies are simply ignored and/or not properly addressed. Utilizing the registered power spectrum of photocurrent, we introduce an LDF signal processing approach suitable for expanding of diagnostic capabilities of the technique. In particular, we demonstrate that it is possible to determine how the oscillations of blood ow (cardiac, breathe, myogenic, etc.) are distributed along the Doppler shift frequency. Wavelet analysis is utilized to extract the oscillations corresponded to the particular frequency sub-bands of blood perfusion. The main purpose of this study is to identify influence of local pressure by fiber optic probe on cardiac oscillations and their distribution along frequency of Doppler shift.

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Igor O. Kozlov, Evgeny A. Zherebtsov, Mikhail A. Mezentsev, Valery V. Shupletsov, Elena V. Potapova, Angelina I. Zherebtsova, Viktor V. Dremin, Andrey V. Dunaev, and Igor V. Meglinski "Analysis of changes in blood flow oscillations under different probe pressure using laser Doppler spectrum decomposition", Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 110791Q (22 July 2019); https://doi.org/10.1117/12.2527040

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