Use of carbon nanodots for visualization of the degenerative area of aricular cartilage

D. I. Kvasniuk; A. P. Maksimyak; P. P. Maksimyak

doi:10.1117/12.2529459

9 September 2019 Use of carbon nanodots for visualization of the degenerative area of aricular cartilage

D. I. Kvasniuk, A. P. Maksimyak, P. P. Maksimyak

Proceedings Volume 11087, Biosensing and Nanomedicine XII; 1108715 (2019) https://doi.org/10.1117/12.2529459
Event: SPIE Nanoscience + Engineering, 2019, San Diego, California, United States

Abstract

We investigated the effectiveness of the penetration of CNDs of various sizes into the articular cartilage of various degrees of degeneration affected by osteoarthritis. We performed quantitative evaluations by the intensity of the fluorescent image of the degenerated area of the articular cartilage in vitro. Using colorimetric MTT assay, we found that our CNDs did not have cytotoxic effects on the cellular level in vitro, and this allowed us to emphasize the prospects for using these nanoparticles as dyes for a considerable amount of observation time.

Citation Download Citation

D. I. Kvasniuk, A. P. Maksimyak, and P. P. Maksimyak "Use of carbon nanodots for visualization of the degenerative area of aricular cartilage", Proc. SPIE 11087, Biosensing and Nanomedicine XII, 1108715 (9 September 2019); https://doi.org/10.1117/12.2529459

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