Towards a super-resolution structured illumination microscope based on an array of nanoLEDs

Nil Franch; Joan Canals; Victor Moro; Oscar Alonso; Sergio Moreno; Anna Vilà; Joan Daniel Prades; Jan Gülink; Hutomo Suryo Wasisto; Andreas Waag; Ángel Diéguez

doi:10.1117/12.2529258

9 September 2019 Towards a super-resolution structured illumination microscope based on an array of nanoLEDs

Nil Franch, Joan Canals, Victor Moro, Oscar Alonso, Sergio Moreno, Anna Vilà, Joan Daniel Prades, Jan Gülink, Hutomo Suryo Wasisto, Andreas Waag, Ángel Diéguez

Author Affiliations +

Proceedings Volume 11105, Novel Optical Systems, Methods, and Applications XXII; 111050O (2019) https://doi.org/10.1117/12.2529258
Event: SPIE Optical Engineering + Applications, 2019, San Diego, California, United States

Abstract

This work presents a first prototype for a new approach to microscopy: a system basing its resolving power on the light emitters instead of the sensors, without using lenses. This new approach builds on the possibility of making LEDs smaller than current technology sensors, offering a new approach to microscopy we plan on developing towards superresolution. The microscope consists on a SPAD based camera, a 8x8 LED array with 5x5 μm LEDs distributed with a pitch of 10 μm, and discrete driving electronics to control them. We present simulations of the system, as well as the first microscope prototype implementing the method, and the results obtained through it.

Citation Download Citation

Nil Franch, Joan Canals, Victor Moro, Oscar Alonso, Sergio Moreno, Anna Vilà, Joan Daniel Prades, Jan Gülink, Hutomo Suryo Wasisto, Andreas Waag, and Ángel Diéguez "Towards a super-resolution structured illumination microscope based on an array of nanoLEDs", Proc. SPIE 11105, Novel Optical Systems, Methods, and Applications XXII, 111050O (9 September 2019); https://doi.org/10.1117/12.2529258

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