Research progress of coronary artery calcification based on optical coherence tomography

Na Qin; Jingbo Wang; Danni Liu; Yana Liu; Lin Huang; Qin Li

doi:10.1117/12.2537772

19 November 2019 Research progress of coronary artery calcification based on optical coherence tomography

Na Qin, Jingbo Wang, Danni Liu, Yana Liu, Lin Huang, Qin Li

Proceedings Volume 11186, Advanced Optical Imaging Technologies II; 111861D (2019) https://doi.org/10.1117/12.2537772
Event: SPIE/COS Photonics Asia, 2019, Hangzhou, China

Abstract

Optical coherence tomography (OCT) is a new medical imaging technology that developed at the end of the 20th century after X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and intravascular ultrasound (IVUS). It is called “optical biopsy” technology with the advantages of no radiation, simple structure and high resolution that can reach ten times that of IVUS. However, OCT also has the disadvantage of insufficient depth of detection that only a few millimeters and imaging speed. Even so, OCT can be used in combination with microscopes, medical catheters and endoscopes; therefore, it has broad application prospects in the field of biomedicine. The OCT system is simple in structure, mainly Michelson interferometer. Using the principle of optical coherence imaging, it detects the back-reflecting or scattering signals of incident light at different depths of biological tissue to obtain the surface and subsurface imaging of transparent or opaque substances. The combination of OCT and endoscopy extends the use of OCT to the diagnosis of cardiovascular diseases, which is called intravascular optical coherence tomography (IVOCT). It enables rapid visualization of microscopic images of vascular cross sections and is a powerful tool for clinical detection of coronary atherosclerosis, in which coronary artery calcification is a common problem in the clinic and is closely related to cardiovascular diseases. This review will briefly introduce the principle of OCT technology and its application in cardiovascular diseases, and focus on the research progress of detection of coronary artery calcification based on OCT technology.

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Na Qin, Jingbo Wang, Danni Liu, Yana Liu, Lin Huang, and Qin Li "Research progress of coronary artery calcification based on optical coherence tomography", Proc. SPIE 11186, Advanced Optical Imaging Technologies II, 111861D (19 November 2019); https://doi.org/10.1117/12.2537772

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KEYWORDS

Optical coherence tomography

Arteries

Intravascular ultrasound

Magnetic resonance imaging

Tissue optics

X-ray computed tomography

Biopsy

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