The optimization criteria for resolution improvement in a lens-free on-chip digital holographic microscope

Jialin Zhang; Qian Chen; Jiasong Sun; Chao Zuo

doi:10.1117/12.2548538

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16 October 2019 The optimization criteria for resolution improvement in a lens-free on-chip digital holographic microscope

Jialin Zhang, Qian Chen, Jiasong Sun, Chao Zuo

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Proceedings Volume 11205, Seventh International Conference on Optical and Photonic Engineering (icOPEN 2019); 112050C (2019) https://doi.org/10.1117/12.2548538
Event: Seventh International Conference on Optical and Photonic Engineering (icOPEN 2019), 2019, Phuket, Thailand

Abstract

The typical lens-free on-chip digital holographic microscopy (LFOCDHM) as a modern imaging technique produce compromised imaging resolution that far below the ideal coherent diffraction limit. At least five major factors may contribute to this limitation, namely, the sample-to-sensor distance, spatial and temporal coherence of the illumination, finite pixel size of the sensor, and finite extent of the image sub-field-of-view used for the reconstruction. In this paper, we derive five transfer function models that account for all these physical effects on the imaging resolution of LFOCDHM. The theoretical resolution limit of a given LFOCDHM system can also be predicted. Besides this, we provide a useful guide to the selection of different system parameters for the optimization of the imaging resolution when designing a new LFOCDHM system.

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Jialin Zhang, Qian Chen, Jiasong Sun, and Chao Zuo "The optimization criteria for resolution improvement in a lens-free on-chip digital holographic microscope", Proc. SPIE 11205, Seventh International Conference on Optical and Photonic Engineering (icOPEN 2019), 112050C (16 October 2019); https://doi.org/10.1117/12.2548538

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