Rapid optical spectroscopic quantification and mapping of human epicardial adipose tissue and lesion deposition (Conference Presentation)

Rajinder P. Singh-Moon; Diego Song Cho; Agastya Vaidya; Charles C. Marboe; Elaine Y. Wan; Christine P. Hendon

doi:10.1117/12.2546856

9 March 2020 Rapid optical spectroscopic quantification and mapping of human epicardial adipose tissue and lesion deposition (Conference Presentation)

Rajinder P. Singh-Moon, Diego Song Cho, Agastya Vaidya, Charles C. Marboe, Elaine Y. Wan, Christine P. Hendon

Author Affiliations +

Proceedings Volume 11215, Diagnostic and Therapeutic Applications of Light in Cardiology 2020; 112150G (2020) https://doi.org/10.1117/12.2546856
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Epicardial catheter ablation has been increasingly recognized as an important adjunct in treating ventricular arrhythmias unamenable by endocardial ablation alone. The presence of epicardial adipose tissue (EAT) is a primary cause for ineffective ablation energy delivery and electrogram misinterpretation. To address this need, we propose a catheter-based near-infrared spectroscopic technique for mapping EAT and lesion deposition, and validate it within excised human donor hearts. We introduce a new parameter, the adipose contrast index (ACI), for rapid lipid assessment. Strong correspondence was observed between values derived from interpolated 3-dimensional ACI maps and histologically-determined EAT layer thickness (Pearson’s, R = 0.903).

Conference Presentation

Citation Download Citation

Rajinder P. Singh-Moon, Diego Song Cho, Agastya Vaidya, Charles C. Marboe, Elaine Y. Wan, and Christine P. Hendon "Rapid optical spectroscopic quantification and mapping of human epicardial adipose tissue and lesion deposition (Conference Presentation)", Proc. SPIE 11215, Diagnostic and Therapeutic Applications of Light in Cardiology 2020, 112150G (9 March 2020); https://doi.org/10.1117/12.2546856

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