Considerations for NIR-I and short-wave infrared (SWIR) fluorescence imaging within a clinical operating room

B. K. Byrd; J. A. Paydarfar; D. J. Wirth; L. J. Tafe; K. S. Samkoe; K. D. Paulsen; S. C. Davis

doi:10.1117/12.2543869

24 February 2020 Considerations for NIR-I and short-wave infrared (SWIR) fluorescence imaging within a clinical operating room

B. K. Byrd, J. A. Paydarfar, D. J. Wirth, L. J. Tafe, K. S. Samkoe, K. D. Paulsen, S. C. Davis

Author Affiliations +

Proceedings Volume 11222, Molecular-Guided Surgery: Molecules, Devices, and Applications VI; 112220T (2020) https://doi.org/10.1117/12.2543869
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Short-wave infrared (SWIR/NIR-II) fluorescence imaging has received increased attention for use in fluorescence-guided surgery (FGS) due to the potential for higher resolution imaging of subsurface structures and reduced autofluorescence compared to conventional NIR-I imaging. As with any fluorescence imaging modality introduced in the operating room, an appropriate accounting of contaminating background signal from other light sources in the operating room is an important step. Herein, we report the background signals in the SWIR and NIR-I emitted from commonly-used equipment in the OR, such as ambient and operating lights, LCD screens and surgical guidance systems. These results can guide implementation of protocols to reduce background signal.

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B. K. Byrd, J. A. Paydarfar, D. J. Wirth, L. J. Tafe, K. S. Samkoe, K. D. Paulsen, and S. C. Davis "Considerations for NIR-I and short-wave infrared (SWIR) fluorescence imaging within a clinical operating room", Proc. SPIE 11222, Molecular-Guided Surgery: Molecules, Devices, and Applications VI, 112220T (24 February 2020); https://doi.org/10.1117/12.2543869

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