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9 March 2020 Functional brain mapping in preschool-age children with high density diffuse optical tomography (Conference Presentation)
Kalyan Tripathy, Alexa M. Svoboda, Mariel L. Schroeder, Andrew K. Fishell, Edward J. Richter, Sean Rafferty, Christopher Tracy, Zachary E. Markow, Muriah D. Wheelock, Adam T. Eggebrecht, Joseph P. Culver
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Proceedings Volume 11226, Neural Imaging and Sensing 2020; 112260E (2020) https://doi.org/10.1117/12.2546817
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
High density diffuse optical tomography (HD-DOT) combines logistical advantages of fNIRS with enhanced image quality, validated extensively against fMRI in adults and neonates. However, HD-DOT is yet to be evaluated in preschool-age children. Here we present an HD-DOT system optimized for preschoolers, including a 128-source by 125-detector console, light-weight fiber optics, and an expanded field-of-view. We validated the system by mapping cortical activations during visual, auditory, and motor tasks in adults. We then imaged children while they watched movies, finding reproducible patterns of brain activity and showing that feature regressors can map functionally specific regions from movie-viewing data in preschoolers.
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Kalyan Tripathy, Alexa M. Svoboda, Mariel L. Schroeder, Andrew K. Fishell, Edward J. Richter, Sean Rafferty, Christopher Tracy, Zachary E. Markow, Muriah D. Wheelock, Adam T. Eggebrecht, and Joseph P. Culver "Functional brain mapping in preschool-age children with high density diffuse optical tomography (Conference Presentation)", Proc. SPIE 11226, Neural Imaging and Sensing 2020, 112260E (9 March 2020); https://doi.org/10.1117/12.2546817
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KEYWORDS
Brain mapping
Diffuse optical tomography
Brain
Image quality
Imaging systems
Neuroimaging
Functional magnetic resonance imaging
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