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9 March 2020 Multifractal OCT for optical detection of retinal function (Conference Presentation)
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Abstract
Herein, we report use of near-infrared low-coherent light for non-contact, label-free in-vivo detection of retinal activity in response to visual illumination. Our multifractal phase-OCT employ phase/multifractal analysis to decipher layer specific cellular activity during visual stimulation to assess the functional state of retina. Our OCT-based interferometric technique coupled with in-depth multifractal analysis differentiated retinal activities between wild-type and mice with retinal dystrophy. Our findings open up possibility of clinical translation of multifractal phase-OCT for non-contact label free evaluation of retina health, progression of retinal dystrophies, and as well as for monitoring functional recovery after therapy.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Subrata Batabyal, Sanghoon Kim, Michael Carlson, Weldon W. Wright, and Samarendra K. Mohanty "Multifractal OCT for optical detection of retinal function (Conference Presentation)", Proc. SPIE 11227, Optogenetics and Optical Manipulation 2020, 112270J (9 March 2020); https://doi.org/10.1117/12.2547004
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