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9 March 2020 Adaptive glasses-assisted Full-Field OCT for SNR enhanced 3D high-resolution retinal imaging (Conference Presentation)
Pedro Mecê, Jules Scholler, Kassandra Groux, Mathias Fink, Kate Grieve, Claude Boccara
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Proceedings Volume 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV; 112281O (2020) https://doi.org/10.1117/12.2544277
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
To achieve 3D high-cellular resolution, a great effort, in the past years, was made to develop Adaptive Optics (AO)-OCT systems. However, such systems require quite complex, expensive and cumbersome hardware, making clinical transfer challenging. Recently, we demonstrated that the use of spatially incoherent illumination in Time-Domain Full-Field (FF)-OCT offers a valuable advantage: the lateral resolution is almost insensitive to ocular aberrations that only affect the FF-OCT signal level. We took advantage of this property to image in-vivo photoreceptor mosaic without using an AO technique. Nevertheless, the FF-OCT technique was still facing some challenges in providing consistent and reproducible images, mainly due to axial eye motion and reduced signal level. Here, we present the Adaptive Glasses-assisted FF-OCT, where an adaptive lens is placed just in front of the eye, like spectacles, enabling correction of the first 10 Zernike polynomials, increasing the FF-OCT signal level.
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Pedro Mecê, Jules Scholler, Kassandra Groux, Mathias Fink, Kate Grieve, and Claude Boccara "Adaptive glasses-assisted Full-Field OCT for SNR enhanced 3D high-resolution retinal imaging (Conference Presentation)", Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 112281O (9 March 2020); https://doi.org/10.1117/12.2544277
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KEYWORDS
Adaptive optics
Eye
3D image enhancement
3D image processing
Glasses
Optical coherence tomography
Retinal scanning
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