Development of HR-SD-OCT system using supercontinuum light source and its application in detecting nanoscale changes

Rajib Dey; Yi Zhou; Nandan Das; Sergey Alexandrov; Andrew Nolan; Kai Neuhaus; Martin Leahy

doi:10.1117/12.2543398

21 February 2020 Development of HR-SD-OCT system using supercontinuum light source and its application in detecting nanoscale changes

Rajib Dey, Yi Zhou, Nandan Das, Sergey Alexandrov, Andrew Nolan, Kai Neuhaus, Martin Leahy

Author Affiliations +

Proceedings Volume 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV; 1122830 (2020) https://doi.org/10.1117/12.2543398
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

In biomedical optics, Optical Coherence Tomography (OCT) is an emerging optical imaging modality during the last three decades. OCT can perform high resolution, cross-section imaging of the internal microstructure in biological tissues by measuring echoes of backscattered light. We have developed a broadband, high-resolution spectral domain OCT system whose central wavelength is 1300 nm with bandwidth ~400 nm. Theoretical axial resolution of the system is ~3.71 μm and experimentally we get ~5 μm in air. Furthermore, we will apply this system for nano-sensitive detection and visualization in varieties of biological tissues.

Citation Download Citation

Rajib Dey, Yi Zhou, Nandan Das, Sergey Alexandrov, Andrew Nolan, Kai Neuhaus, and Martin Leahy "Development of HR-SD-OCT system using supercontinuum light source and its application in detecting nanoscale changes", Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 1122830 (21 February 2020); https://doi.org/10.1117/12.2543398

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