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9 March 2020 Fast and sensitive delineation of brain tumor with clinically compatible moxifloxacin labeling and confocal microscopy (Conference Presentation)
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Abstract
Surgical resection is the primary treatment for malignant brain tumors. This procedure has a dilemma—aggressive surgical resection tends to extend patient survival; however, it also increases the risk of neurological deficiencies. Current medical imaging methods are not sensitive and their interpretation largely depend on surgeon’s impression. High-speed cellular imaging method by using clinically applicable moxifloxacin was demonstrated for fast and sensitive tumor-detection. The detailed cytoarchitecture of brain tumor mouse model and malignant human brain tumors was revealed. This study showed the potential and feasibility of moxifloxacin-based confocal microscopy as a surgery-guiding method for tumor removal.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Seunghun Lee, Wonyeong Park, Seonghan Kim, Hoonchul Chang, Bumju Kim, Won Hyuk Jang, Younghoon Shin, Myoung Joon Kim, Euiheon Chung, Eui Hyun Kim, Kyung Hwa Lee, and Ki Hean Kim "Fast and sensitive delineation of brain tumor with clinically compatible moxifloxacin labeling and confocal microscopy (Conference Presentation)", Proc. SPIE 11229, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVIII, 112291F (9 March 2020); https://doi.org/10.1117/12.2546056
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