Fast stimulated Raman and second harmonic generation imaging for intraoperative gastro-intestinal cancer detection (Conference Presentation)

Hervé Rigneault; Barbara Sarri; Xavier Audier; Julien Wojak; Fabrice Caillol; Flora Poizat; Marc Giovannini

doi:10.1117/12.2544989

9 March 2020 Fast stimulated Raman and second harmonic generation imaging for intraoperative gastro-intestinal cancer detection (Conference Presentation)

Hervé Rigneault, Barbara Sarri, Xavier Audier, Julien Wojak, Fabrice Caillol, Flora Poizat, Marc Giovannini

Author Affiliations +

Proceedings Volume 11236, Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry; 112360H (2020) https://doi.org/10.1117/12.2544989
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

We present advances in coherent Raman imaging for gastrointestinal cancer detection. We use stimulated Raman scattering (SRS) combined with second harmonic generation (SHG) to reveal cell nuclei, cytoplasm and collagen simultaneously in human tissues. Cell nuclei, cytoplasm and extra cellular matrix can be visualized in real time with image quality similar to conventional histology.

Conference Presentation

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Hervé Rigneault, Barbara Sarri, Xavier Audier, Julien Wojak, Fabrice Caillol, Flora Poizat, and Marc Giovannini "Fast stimulated Raman and second harmonic generation imaging for intraoperative gastro-intestinal cancer detection (Conference Presentation)", Proc. SPIE 11236, Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry, 112360H (9 March 2020); https://doi.org/10.1117/12.2544989

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