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21 February 2020 Effects of normobaric hypoxia on cardiac mechanical function using seismocardiography
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This study investigated the effects of normobaric hypoxia on mechanical cardiac function during resting and short-term moderate intensity exercise. The cardiac contraction force and ventricular twist of eleven healthy male participants (24±5 years, 176±3cm, 76±9kg) were assessed using seismocardiography (SCG). The SCG was placed superficially to the sternum, 1 cm above the Xiphoid process. An isometric squat-stand maneuver performed at 0.05 Hz for 5 minutes was used as the exercise stimulus. Participants began by resting supine for 30-minutes under normobaric normoxia (712mmHg, 577m, 19.8% oxygen), followed by the squat-stand maneuver. Participants repeated the supine and squat-stand maneuver in a normobaric hypoxic (712mmHg, ~2750m, 14.8% oxygen) environmental simulation chamber. SCG was measured for 30 seconds at the end of normoxic rest (T1), end of normoxic squat-stands (T2), end of hypoxic rest (T3), and end of hypoxic squat-stands (T4). An average of 5 cardiac beats from the SCG were analyzed to determine contraction force and ventricular twist (milligravity, mG). No significant differences were found under resting conditions between T1 and T3 (13±2, 15±3 mG). Furthermore, no significant differences were found comparing squat-stands between normoxia (T2, 35±6 mG) and hypoxia (T4, 45±9 mG), although there were trends showing an increase in contraction force during hypoxia (p=0.2). Ventricular twist mechanics showed similar responses. These results suggest that acute shortduration normobaric hypoxia had no significant effect on the contractility and ventricular twist mechanics of the heart after a moderate-intensity squat-stand exercise. This shows that mechanical cardiac function can be assessed using SCG.
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© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Taylor A. Teckchandani, David Mac Quarrie, Jyotpal Singh, and J. Patrick Neary "Effects of normobaric hypoxia on cardiac mechanical function using seismocardiography", Proc. SPIE 11237, Biophotonics in Exercise Science, Sports Medicine, Health Monitoring Technologies, and Wearables, 112370E (21 February 2020);




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