Presentation
9 March 2020 Time-domain diffuse correlation spectroscopy of turbid media with mixed dynamics (Conference Presentation)
Author Affiliations +
Abstract
We apply time-domain diffuse correlation spectroscopy (TD DCS) to quantify dynamics in samples with mixed dynamics, containing both static and dynamic scatterers. We demonstrate that standard TD DCS processing is incapable to properly quantify dynamics at short source-detector distances due to the strong influence of the static component. To solve this problem, we introduce a novel model, which allows recovering the autocorrelation decay of the dynamic part properly. We then apply this novel approach in humans in vivo. We recovered the blood flow index of the leg muscle covered by the thin static turbid layer during the cuff occlusion challenge.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Dawid Borycki, Saeed Samaei, Michal Kacprzak, Piotr Sawosz, and Adam Liebert "Time-domain diffuse correlation spectroscopy of turbid media with mixed dynamics (Conference Presentation)", Proc. SPIE 11239, Dynamics and Fluctuations in Biomedical Photonics XVII, 1123906 (9 March 2020); https://doi.org/10.1117/12.2545598
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KEYWORDS
Spectroscopy

Computer programming

Cortical activation

Neuroimaging

Neurovascular coupling

Photodetectors

Photon counting

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