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Optical coherence tomography (OCT) is a promising research tool for non-invasive imaging of biological tissues. OCT can be used to capture images of the beating Drosophila heart in vivo with micrometer resolution and video-rate imaging speed. Due to its non-invasiveness nature, OCT enables longitudinal imaging of developing flies through the entire life cycle of the insect. Combined with non-invasive optogenetic pacing, this forms a powerful research platform to study developmental biology.
Chao Zhou
"Optical imaging and pacing of drosophila heart function (Conference Presentation)", Proc. SPIE 11239, Dynamics and Fluctuations in Biomedical Photonics XVII, 112390T (9 March 2020); https://doi.org/10.1117/12.2554831
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Chao Zhou, "Optical imaging and pacing of drosophila heart function (Conference Presentation)," Proc. SPIE 11239, Dynamics and Fluctuations in Biomedical Photonics XVII, 112390T (9 March 2020); https://doi.org/10.1117/12.2554831